NUTLEY, N.J., - A federal court jury in Muskogee, Okla., has unanimously denied a woman's claim that the popular acne drug Accutane caused her to suffer from depression.

Carla Gray of Ada, Okla., claimed that Accutane's maker, Hoffman-La Roche Inc., failed to provide adequate warnings about depression on the product packaging. Gray sought over $3 million in compensatory damages, although depression has been mentioned on the product package insert since 1985.

In the 20 years that Accutane has been available to patients with severe recalcitrant nodular acne, there has been no scientific evidence that shows that Accutane causes depression, despite numerous studies. "Even the plaintiff's own experts had to admit that the theory that Accutane can cause depression is not accepted in the scientific community," said Roche's attorney, Harry Woods.

In a related story, the family of a 15-year-old boy who crashed a stolen plane into a Tampa high-rise building is suing Roche for $70 million, accusing the medicine of prompting her son's suicide.

The lawsuit filed Monday claims the drug caused severe psychosis in Charles Bishop, who died Jan. 5 after leaving behind a note expressing sympathy for Osama bin Laden, and also expressing support for the Sept. 11 attacks.

In an interview aired Tuesday on the "Today" show, the boy's mother, Julie Bishop, said her son had showed no signs of depression and that "this child was a happy, well-balanced, forward-thinking child who had a great deal to live for. This was psychotic and the only conclusion we have been able to draw is the Accutane poisoned him."

A Hoffman-La Roche spokeswoman said the company was unaware of the lawsuit, but the company does not believe the drug is dangerous. And while Accutane does carry a warning about depression and suicide, the company points to statistics showing sufferers of severe acne and teenagers, the main users of the drug, generally have higher suicide rates.

The Food and Drug Administration says 147 people taking Accutane either committed suicide or were hospitalized for suicide attempts from 1982 to May 2000. An estimated 13 million patients have used Accutane since its debut in 1982. An autopsy found no trace of Accutane in Bishop's blood, but attorneys for the family say so much blood was lost in the crash that the test may not have been useful.